Pogba is out with hamstring and thigh issues picked up within the Three-Zero win over Basel previous this month.
United have persisted plenty of long-term injury lay offs in fresh months, with Ibrahimovic and Rojo nonetheless operating on returning to complete health.
Phil Jones and Antonio Valencia have additionally come again from accidents, even supposing sooner than anticipated.
There was once hope Pogba’s injury wouldn’t be as critical as first concept.
But Mourinho admits the France global is dealing with a while at the sidelines.
“Pogba cannot play tomorrow (against Crystal Palace) and it’s not an injury that I can have the hope with Valencia or Jones,” Mourinho mentioned.
“Long term injuries I don’t speak about them, Ibra, Pogba and Rojo.”
United host Palace the next day (3pm) hoping to soak up best spot within the Premier League.
Mourinho stored plenty of avid gamers again when United travelled to CSKA Moscow within the Champions League in midweek.
Discussing his facet’s health woes, the boss added: “We have to coach and make selections after coaching however I am hoping one of the most avid gamers that couldn’t play in Moscow perhaps now not they all however confidently some can get well.
“Tomorrow some will likely be out finally the wounds we had I am hoping that I will be able to have some avid gamers to be had the next day.”